Opalite is an AI medical interpreter with real-time interpretation in 150+ languages, EHR documentation, and flat-rate pricing. Read the full review.
Researched and fact-checked by Bartu Cavusoglu · Updated October 26, 2026
Opalite is an AI medical interpreter designed for healthcare organizations. It provides real-time interpretation in more than 150 languages and dialects, and the company positions it as a replacement for, or complement to, human interpreter services that bill by the minute. It is available around the clock with no wait time.
Opalite Health is backed by Y Combinator and based in the San Francisco Bay Area. The company was co-founded by Cathleen Kuo, MD, a physician and AI healthcare researcher, and Alex Mehregan, a former Apple engineer. Its stated mission is that language should never decide whether a patient is heard, correctly diagnosed, or safely treated.
Opalite performs speech-to-speech interpretation in both directions. A clinician speaks in English and the patient hears the message in their language, and the reply is interpreted back. It runs on phones, tablets, and computers that teams already use, on iOS, Android, Windows, and Mac, so no dedicated hardware is required.
Opalite Guardian checks every sentence during the conversation so errors can be caught before they reach the patient. Encounter records are then written into the customer's EHR. The same service works in person, over video platforms such as Zoom and Microsoft Teams, and over any phone line, including landlines.
The core capability is real-time interpretation in 150+ languages and dialects, from Spanish and Haitian Creole to Amharic and Swahili. Guardian adds sentence-level safety checks, and the company cites a blinded comparison against certified interpreters by physician-researchers that found over 90% fewer errors in Spanish, Mandarin, and Cantonese.
On the workflow side, Opalite documents encounters directly in the EHR using FHIR R4, with SMART on FHIR and OAuth 2.0 where supported. Security materials list HIPAA-compliant safeguards, SOC 2 Type II attested controls, Section 1557-ready language-access workflows, and a business associate agreement for every customer.
Opalite is an AI medical interpreter for healthcare. It provides real-time, two-way speech interpretation in 150+ languages and dialects, with sentence-level safety checks and EHR documentation. It is designed for hospitals, health centers, clinics, home health, and telehealth.
Opalite does not publish prices. It uses a flat, predictable rate scoped to the number of sites, departments, or overall usage, instead of a per-minute meter. A demo call is followed by a pricing proposal.
No. The company states that Opalite is a flat rate rather than a per-minute meter, so costs do not rise with every encounter. It contrasts this with a $3.95 per minute pay-as-you-go human interpreter rate from LanguageLine.
Opalite supports more than 150 languages and dialects. Interpretation runs in both directions in real time and is available 24/7. Examples shown include Spanish, Vietnamese, Haitian Creole, Mandarin, Cantonese, Arabic, and Korean.
Yes. Opalite writes encounter records directly into the EHR a customer already uses, with integration based on FHIR R4 and SMART on FHIR and OAuth 2.0 where supported. The pages reviewed do not name specific EHR vendors.
The company states that the platform is HIPAA compliant and that its controls are SOC 2 Type II attested. Every customer receives a business associate agreement at no extra charge, and trust-center documentation is available on request.
Opalite says it can be live in as little as one day. Setup involves providing credentials and permissions, a 20-minute provider training session or short videos, and then starting with one team before expanding.
Opalite suits healthcare organizations that serve many patients with limited English proficiency and want predictable interpretation costs. This includes hospitals, community health centers, clinics, home health agencies, telehealth providers, and EMS.